Endocrine Abstracts

Introduction: Remission by complete surgical tumour removal is not achieved in all patients with acromegaly and a subset of patients remain on long-term pharmacological treatment. Repeated surgery or targeted radiation therapy can be considered in patients with residual or recurrent tumour. Identification of residual or recurrent tumour available for surgical treatment can be challenging, and underreporting may lead to a loss in treatment opportunity. The aim of the present st...

Background: Surgery is accepted as first line treatment of somatotroph macroadenomas with involvement of the optic chiasm. However, during recent years somatostatin analogues (SA) have increasingly been used as primary treatment improving ultimate cure rate, as SA’s have anti-proliferative effects in most tumours. We demonstrate here positive effect of subacute/acute SA treatment on tumour shrinkage and chiasm decompression in two recently diagnosed acromegalic patients.<...